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What to expect

Our team of healthcare experts is testing an investigational drug to see if it can control your blood sugar without impacting your weight. The investigational drug will be compared with an approved drug for people with type 2 diabetes and a placebo. A placebo looks like the investigational drug but does not have any effect on your body.

The investigational drug, approved drug and placebo come in tablet form. You will be asked to take 1 tablet orally (by mouth) with a glass of water every day for 24 weeks.

If you take part, you will join one of three dose groups. You will have a 2 in 3 chance of receiving the investigational drug and a 1 in 3 chance of receiving the approved drug or placebo. You cannot choose which group you will join.

The study could last up to 32 weeks and is made up of 3 parts:

Part 1: Screening (4 weeks) – you will have tests at your nearest study center to see whether you can take part

Part 2: Study treatment (24 weeks) – if you qualify, you will take the investigational drug, approved drug or placebo

Part 3: Follow-up (4 weeks) – you will be asked to return to the study center 2 more times to check on your health

Over the course of the study, you will be asked to attend the study center approximately 10 times. There may be additional visits required, which will be decided by the study doctor.

What happens at the study center?

During visits to the study center, you will have tests and be asked questions to see how you are responding to study treatment. The following tests will occur at some point in the study:

A machine will record the rate and rhythm of your heart beats through small patches attached to your chest, arms and legs.

You will be asked to pee into a container to check how well your kidneys are working.

A sample of blood will be collected through a vein in your arm to check your cholesterol levels.

A small drop of blood will be collected using a tiny needle to check your cholesterol levels.

You will be asked to complete several questionnaires to see how type 2 diabetes is affecting your life.

360

participants

32

weeks

24

countries

10

visits